Our team is interested by the biophysics and soft matter of soft particles and blood rheology. We study the behaviour of soft particles such as red blood cells, vesicles and capsules under flow to gain insight into fundamental phenomena, biological processes and beyond into the rheological of suspensions of soft particles. These particles are drops bounded by a thin membrane with specific mechanical properties : see the following document.
Applications are in various domains such as biology, medecine, food, cosmetics and pharmaceutics. See in the following some examples of studies with an included video.
Microcirculation of a vesicle : comparison between theory and experiments
Wrinkles along a capsule moving inside a narrow cappilary - side and front video Experimental video. under construction
Motion of a vesicle inside a narrow capillary Experimental video. under construction
propositions de thèses en matière molle et biomécanique/biophysique :
This year, we have three proposals : two possibilities of PhD and one postdoc position.
POSTDOC : Modelling of the dynamics of a soft capsule/vector in blood This postdoc is one year renewable one time. The research project is numerical and theoretical.
French version under request. Seethe images of i) a tether and pearls, ii) a comparison between experimental and numerical shapes and iii) a slipper vesicle in a Poiseuille flow.
Numerical/Theoretical PhD : Modélisation de la dynamique de nanovecteurs dans le sang Numerical and theoretical project on polymersomes, capsules and other nanovectors.
See the experimental image of a capsule with wrinkles.
Experimental PhD : Collective phenomena in blood - Phenomenon of margination Experimental project on margination.
G. Boedec, M. Leonetti and M. Jaeger, 3D vesicle dynamics simulations with a linearly triangulated surface, J. Comp. Phys. 230 (2011) 1020-1034
G. Boedec, M. Jaeger and M. Leonetti, Sedimentation-induced tether on a settling vesicle, Phys. Rev. E Rapid Com. 88 (2013) 010702(R)
G. Boedec, M. Jaeger and M. Leonetti, Settling of a vesicle in the limit of quasispherical shapes, J. Fluid Mech. 690 (2012) 227-261.
S. Chatkaew, M. Georgelin, M. Jaeger and M. Leonetti, Dynamics of Vesicle Unbinding under Axisymmetric Flow, Phys. Rev. Lett. 103 (2009) 248103
G. Boedec, M. Jaeger and M. Leonetti, Pearling instability of a cylindrical vesicle, to appear in J. Fluid Mech. 2014